基于科学论文和专利信息的基因测序技术领域创新态势分析

目的：了解基因测序技术的国际创新态势，以促进我国精准医学以及基因测序技术的发展。方法：以科学论文和专利信息作为基础数据，构建创新态势研究分析框架，从科学研究和技术研发两方面对基因测序技术的国际研发态势进行综合分析。结果：基因测序技术的科学研究和技术研发主题主要集中在肿瘤诊疗、植物基因组测序、HIV病毒和胃肠道菌群的鉴别等方面，单细胞基因组扩增新技术（MALBAC）极大的推动了基因测序技术的发展。结论：我国基因测序技术的科学研究和技术研发已处于较为领先的水平。

Scientific literature and patent information-based analysis of innovation situation in gene sequencing technologies

Objective To promote the development of precision medicine and gene sequencing technologies in China by analyzing the innovation situation in gene sequencing technologies. Methods An innovation situation research analysis frame was established with scientific literature and patent information as its basic data. The innovation situation in gene sequencing technologies was analyzed in aspects of scientific research and technical R & D. Results The research on gene sequencing technologies and technical R & D were focused on tumor diagnosis and treatment, plant gene sequencing, identification of HIV and gastrointestinal flora. Single cell genome amplification technology has greatly promoted the development of gene sequencing technologies. Conclusion The level of gene sequencing technologies and technical R & D in China is approaching to that in the world.