细支气管肺泡细胞癌5例临床病理分析

目的探讨肺支气管肺泡细胞癌(bronchioloalveolar carcinoma,BAC)的临床及其病理特点。方法对5例支气管肺泡细胞癌均行外科手术治疗,随访1-6年;同时将手术标本进行病理检查,并复习相关文献。结果病理学表现:肿瘤细胞呈立方状,胞质透亮嗜酸,核异型性明显,核仁显著,可见鞋钉样细胞,肿瘤细胞沿着支气管肺泡生长,肺泡结构完整,未见间质、血管、胸膜浸润。结论支气管肺泡细胞癌预后较好,应与浸润性腺癌鉴别,确诊依赖病理学检查。

Bronchioloalveolar carcinoma:Report of five cases with review of literatures

Objective To investigate the clinicopathological features of bronchioloalveolar carcinoma(BAC)and its behaviour and prognosis.Methods The clinical data was analysed of five case of BAC with review of the literature.Results Microscopically,Cytology shows a cohesive cell group with variable nuclear size,prominent nucleoli and perinucleolar clearing.Cuboidal to columnar shaped cells grow along alveolar walls in a lepidic fashion.Conclusions Prognosis can have a good effect on patients with BAC.BAC is a rare tumor,whose definite diagnosis should be based on the histopathological and immunohistochemical features.Its clinical manifestation should also be taken into account.