深圳市耐药肺结核病诊断治疗现状调查

目的　掌握深圳市耐药肺结核病的诊断及治疗现状 ,为制定防治措施提供依据。方法 对市、区级结核病防治专业机构及传染病院 2002-2003年登记和治疗的耐药肺结核的诊断方法、治疗方案及效果进行调查。结果2002-2003年共治疗耐药肺结核病人 103例 ,但实验室诊断方法不一,治疗方案不合理占28.1% ,对病人未进行全程督导管理。转归队列分析显示 ,治愈率34.9% ,失败率为 30.1% ,丢失率 13.6% ,还有9.7%的病人无法评价。结论 深圳市耐药结核病疫情较严重 ,二线药已广泛使用、急需建立耐药病人治疗和管理常规 ,以控制耐药结核病的流行。

Analysis on the status of diagnosis and treatment of drug resistant tuberculosis patients in Shenzhen

Objective To determine the status of diagnosis and treatment of drug resistant tuberculosis patients in Shenzhen in order to provide evidences for policy makers on TB control.Methods To investigate drug resistant TB patients from city and county level TB dispensaries and infectious disease hospitals on diagnosis,treatment and management situation in 2002-2003.Results 103 drug resistant TB patients had been diagnosed and treated in 2002—2003.The laboratory method selected for diagnosis was different.28.1% of treatment regimens were irrational,direct observed treatment (DOT) was not provided to patients.The cure rate was 34.9%,the failure rate was 30.1%,the default rate was 13.6%.9.7% of cases were not evaluated.Conclusion Epidemical situation of MDR TB is very severer in the city.It is necessary to establish criteria for diagnosis,treatment and management of MDR TB and implement DOTS PLUS tactics to control the prevalence of MDR TB.