| 基于Excel求解静脉注射给药隔室模型参数及药动学参数 |
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| 引用本文： | 袁进,石磊,赵树进. 基于Excel求解静脉注射给药隔室模型参数及药动学参数[J]. 中国药师, 2007, 10(2): 161-163 |
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| 作者姓名： | 袁进 石磊 赵树进 |
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| 作者单位： | 广州军区广州总医院药剂科,广州,510010 |
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| 摘 要： | 目的:基于Excel建立一种简便的计算静脉注射给药药物动力学参数和隔室模型的方法。方法:采用残数法原理,利用Excel统计函数,逐步求解药物动力学参数和隔室模型参数。结果:基于Excel可直观演示静脉注射给药药动学参数和隔室模型参数计算过程,结果与教材一致。结论:基于残数法原理,Excel统计函数可用于临床教学或实验中药物动力学参数计算。
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| 关 键 词： | 残数法 隔室模型 药物动力学 |
| 文章编号： | 1008-049X(2007)02-0161-03 |
| 修稿时间： | 2006-06-19 |
Calculation of Pharmacokinetic Parameters and Compartment Model''s Parameters by Intravenous Injection Based on Excel Function |
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| Yuan Jin,Shi Lei,Zhao Shujin. Calculation of Pharmacokinetic Parameters and Compartment Model''s Parameters by Intravenous Injection Based on Excel Function[J]. China Pharmacist, 2007, 10(2): 161-163 |
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| Authors: | Yuan Jin Shi Lei Zhao Shujin |
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| Affiliation: | Dept. of Pharmacy, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010 ,China |
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| Abstract: | Objective:To find a simple method for calculating pharmacokinetic parameters and compartment model by intravenous injection based on Excel function.Method:The residual method and Excel function were used to solve pharmacokinetic parameters and compartment model parameters gradually.Result:Excel can be used to directly demonstrate calculation process of parameters of phar- macokinetics and compartment model,and which accords to the results of teaching book.Conclusion:Excel function can be used to calculate pharmacokinetic parameters in clinical teaching and experiments. |
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| Keywords: | Excel |
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