Diagnostic value of anti-cyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis |
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| Authors: | Ioannis Alexiou Anastasios Germenis Athanasios Ziogas Katerina Theodoridou Lazaros I Sakkas |
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| Affiliation: | (1) Department of Rheumatology, Thessaly University School of Medicine and Hospital, 412 22 Larisa, Greece;(2) Department of Immunology and Histocompatibility, Thessaly University School of Medicine and Hospital, Larisa, Greece |
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| Abstract: | Background Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been of diagnostic value in Northern European Caucasian patients with rheumatoid arthritis (RA). In these populations, anti-CCP antibodies are associated with the HLA-DRB1 shared epitope. We assessed the diagnostic value of anti-CCP antibodies in Greek patients with RA where the HLA shared epitope was reported in a minority of patients. |
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