| 舒林酸食道支架放疗联合治疗食道癌48例分析 |
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| 引用本文： | 陆华生,钱俊波,陈天敏,王高仁,缪旭东.舒林酸食道支架放疗联合治疗食道癌48例分析[J].中国内镜杂志,2003,9(5):11-12. |
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| 作者姓名： | 陆华生 钱俊波 陈天敏 王高仁 缪旭东 |
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| 作者单位： | 1. 南通医学院二附院消化内科,226001
2. 南通医学院二附院放疗科,226001 |
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| 摘 要： | 目的：探讨一种既能改善食道癌性狭窄所致的吞咽困难，又能抑制肿瘤生长的治疗手段。方法：在1996-1999年期间，采用舒林酸(sulindac)、支架、放疗26例患者，与同期间硒宝康、支架、放疗22例患者进行对照观察，比较两组的吞咽困难积分改善情况和3年存活率。结果：舒林改组与硒宝康组吞咽困难积分无显著差异(P＞0．05)，3年生存率分别为46．5％和22．7％。P＜0．05有显著差异。结论：舒林酸、支架、放疗对晚期食管癌治疗具有较多好疗效，既改善了吞咽困难，又控制肿瘤细胞生长，达到标本兼治的作用。
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| 关 键 词： | 舒林酸 食管癌 食道支架 放射治疗 |
| 修稿时间： | 2002年11月18 |
ANALYSIS OF 48 CASES OF ESOPHAGEAL CANCER TREATED BY SULINDAC STENTS COMBINED RADIOTHERAPY |
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| Lu Huasheng,Qian Junbo,Chen Tianmin,et al..ANALYSIS OF 48 CASES OF ESOPHAGEAL CANCER TREATED BY SULINDAC STENTS COMBINED RADIOTHERAPY[J].China Journal of Endoscopy,2003,9(5):11-12. |
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| Authors: | Lu Huasheng Qian Junbo Chen Tianmin |
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| Institution: | Lu Huasheng,Qian Junbo,Chen Tianmin,et al. Department of Gastroenterology,the Second Affiliated Hospital of Nantong Medical College,Nantong 226001 |
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| Abstract: | Objective: To explore a way of treatment that not only improve the dysphagia and strictures of esophageal cancer but also inhibit the tumour cells growth.Methods: From 1996 to 2000,twenty-six patients were treated with Sulindac,metallic stent and radiotherapy.Twenty-two patients as control group did placebo,metallic stent and radiotherapy. The 3-year surival rate and the dysphagia improved index were analysised in two groups.Results:The 3-year surival rate was significantly higher in Sulindac group than in control group,being 46.5% and 22.7% respectively( P <0.05).The dysphagia index in two groups was no differentiation( P >0.05).Conclusion: Combined with Sulindac, metallic stent and radiotherapy is good choice for non surgery esophageal cancer. |
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| Keywords: | Sulindac Esophageal Cancer Stents Radiotherapy |
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