| 随机单盲对照研究观察托特罗定治疗留置尿管相关膀胱不适的疗效 |
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| 引用本文： | 何云锋,吴小候,唐伟,陈在贤,王德林,尹志康,蒲军,陈刚,张尧. 随机单盲对照研究观察托特罗定治疗留置尿管相关膀胱不适的疗效[J]. 重庆医学, 2011, 40(1). DOI: 10.3969/j.issn.1671-8348.2011.01.007 |
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| 作者姓名： | 何云锋 吴小候 唐伟 陈在贤 王德林 尹志康 蒲军 陈刚 张尧 |
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| 作者单位： | 重庆医科大学附属第一医院泌尿外科; |
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| 摘 要： | 目的探讨托特罗定治疗留置尿管后导致膀胱不适的疗效。方法观察2005年10月至2010年8月由于各种原因留置尿管的患者,对比托特罗定治疗和安慰剂治疗的疗效,采用随机分组选择患者为治疗组或安慰剂组,治疗组口服托特罗定,每次2 mg,每天2次至拔管。结果尿道手术组完成的63例中,治疗组36例发生膀胱不适1例,安慰剂组27例发生膀胱不适7例;前列腺电切组完成的271例中,治疗组164例发生膀胱不适7例,安慰剂组107例发生膀胱不适43例;膀胱肿瘤电切组完成的76例中,治疗组34例均未发生膀胱不适,安慰剂组42例发生膀胱不适9例;输尿管镜组完成的363例中,治疗组217例发生膀胱不适9例,安慰剂组146例发生膀胱不适41例;经皮肾镜组167例中,治疗组72例发生膀胱不适2例,安慰剂组95例发生膀胱不适25例;腔内未操作组完成的88例中,治疗组47例发生膀胱不适4例,安慰剂组41例发生膀胱不适10例。结论托特罗定能够有效控制各种原因留置尿管后引起的膀胱不适症状。
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| 关 键 词： | 膀胱 托特罗定 留置尿管 |
Efficacy of tolterodine for prevention of catheter-related bladder discomfort: a randomized,placebo-controlled,single-blind study |
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| He Yunfeng,Wu Xiaohou,Tang Wei,Chen Zaixian,Wang Delin,Yin Zhikang,Pu Jun,Chen Gang,Zhang Yao. Efficacy of tolterodine for prevention of catheter-related bladder discomfort: a randomized,placebo-controlled,single-blind study[J]. Chongqing Medical Journal, 2011, 40(1). DOI: 10.3969/j.issn.1671-8348.2011.01.007 |
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| Authors: | He Yunfeng Wu Xiaohou Tang Wei Chen Zaixian Wang Delin Yin Zhikang Pu Jun Chen Gang Zhang Yao |
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| Affiliation: | He Yunfeng,Wu Xiaohou,Tang Wei,Chen Zaixian,Wang Delin,Yin Zhikang,Pu Jun,Chen Gang,Zhang Yao(Department of Urology,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China) |
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| Abstract: | Objective To evaluate the efficacy of tolterodine for prevention of catheter-related bladder discomfort.Methods We used tolterodine or placebo to prevent the bladder discomfort caused by the indwelling catheter from Oct.2005 to Aug.2010,the patient took tolterodine 2 mg twice daily or placebo 2 mg twice daily orally,from indwelling catheter to removal of the catheter.The groups included:operation on urethra group,transurethral resection of prostate group,transurethral resection of bladder tumor group,operat... |
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| Keywords: | bladder tolterodine indwelling catheter |
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