胃癌癌周淋巴结状态与胃癌的关系分析

目的 探索胃癌病人淋巴结转移个数及率与胃癌病人预后以及病理参数之间的关系。方法 对174例有淋巴结转移的胃癌病人行胃癌根治术加D2或D3淋巴结清扫，分析淋巴结转移阳性个数、率、部位与预后及病理参数之间的关系。结果 胃癌根治术后（D2、D3）5年生存率为29．59％（50例）。阳性淋巴结个数为1－5个5年生存率为46．47％（33例） ，大于5个的17．35％（17例）（P＜0．005）；阳性淋巴结率在1％－20％的5年生存率为70．58％，20％以上5年生存率为11．86％。5年生存率随着阳性淋巴结个数、率增多而呈下降趋势。随着肿瘤浸润加深，淋巴结转移个数、率增高（P＜0．005）。结论 胃癌转移淋巴结状态与胃癌病人预后有相关性，胃癌转移淋巴结个数、转移率可作为简单、 有效的预后指标。

The analysis on relation of gastric lymph node status to prognosis of patients with gastric carcinoma

Objective To study the correlation of the number and ratio of involved lymph nodes and the prognosis of gastric carcinoma .Methods 174 patients with positive gastric lymph nodes were included,they were treated by radical gastrectomy and lymph nodes dissection (D2 or D3)in our department. The number and ratio of metastastic gastric lymph nodes were calculated. Their influence and their interrelation with pathogenic parameters were analyzed. Results The overall 5 year survival rate was 29.59%, and the five year survival rates of patients with 1 20 per cent and more than 20% positive lymph nodes were 70.58%,11.86% respectively, one to five positive lymph nodes and five more were 46.47%,17.35% respectively, the five year survival rate was decreased as the ratio and number of involved lymph nodes increased. Studies also indicated that with the increase of depth of cancer invasion ,the number and ratio of involved lymph node elevated.Conclusions The results shows that the number and ratio of involved lymph nodes correlated to tumour progression and the five survival rate.Perigastric lymph node status can be considered as a simple and effective prognosis factor.