某医院重组人血小板生成素注射液应用合理性评价

目的了解某医院住院病人使用重组人血小板生成素注射液的合理性。方法回顾性抽取2019年1月1日至12月31日蚌埠医学院第二附属医院使用重组人血小板生成素注射液的病人病历126份，从适应证、用法用量、使用疗程等方面进行合理性评价。结果126份病历，56份病历不合理，不合理使用主要是超适应证用药(26例，20.63%)、剂量不适宜(123例，97.62%)和超疗程用药(30例，23.81%)。结论该院重组人血小板生成素注射液临床应用存在超适应证用药、剂量不适宜、超疗程用药问题，需加强医务人员合理用药培训，加大监管和处罚力度，规范合理使用。

Rationality evaluation of recombinant human thrombopoietin injection in a hospital

Objective To investigate the rationality of using recombinant human thrombopoietin injection among inpatients in a hospital.Methods A total of 126 patients who used recombinant human thrombopoietin injection in The Second Affiliated Hospital of Bengbu Medical College from January 1, 2019 to December 31, 2019 were retrospectively selected, and the rationality was evaluated based on the aspects of indication, dosage and course of treatment.Results Among the 126 medical records, 56 cases were unreasonable.The irrational use mainly included over-indication (26 cases, 20.63%), inappropriate dosage (123 cases, 97.62%) and over-course of medication (30 cases, 23.81%).Conclusion Recombinant human thrombopoietin injection in the hospital is used unreasonably in clinical practice in the form of over-indication, inappropriate dosage, over-course of medication. Therefore, it is necessary to strengthen the training of medical personnel on rational drug use, strengthen supervision and punishment to standardize rational use of recombi-nant human thrombopoietin injection.