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新冠病毒奥密克戎变异株的特点与防控措施
引用本文:张佳琦,刘国华,黄建安.新冠病毒奥密克戎变异株的特点与防控措施[J].中国感染控制杂志,2022,21(8):816-822.
作者姓名:张佳琦  刘国华  黄建安
作者单位:1. 南京医科大学附属苏州医院呼吸与危重症医学科(东区), 江苏 苏州 215001;2. 苏州大学附属第一医院呼吸与危重症医学科, 江苏 苏州 215031
基金项目:苏州市科技局计划项目(SYS2020037);苏州市科协研究项目(2020第52号)
摘    要: 自2021年11月新型冠状病毒奥密克戎变异株出现以来,几个月内迅速席卷全球。世界各国都出现了以奥密克戎为主要流行毒株的新一轮疫情,我国香港、深圳、上海等城市也未能幸免。奥密克戎刺突蛋白含有大量突变,具有强大的免疫逃逸能力,对现有的疫苗和抗体相关治疗造成了巨大的威胁。虽然奥密克戎变异株引起的疾病症状较轻,但由于其超高的传播率,全球卫生系统均承受了巨大的压力。本文就奥密克戎变异株的病原学特征、变异来源、传播特征、流行现状及防治措施等方面进行综述,以期为科学防控提供参考。

关 键 词:新型冠状病毒    奥密克戎变异株    新冠肺炎    防控  
收稿时间:2022/5/26 0:00:00

Characteristics, prevention and control measures of SARS-CoV-2 Omicron variant
Jia-qi ZHANG,Guo-hua LIU,Jian-an HUANG.Characteristics, prevention and control measures of SARS-CoV-2 Omicron variant[J].Chinese Journal of Infection Control,2022,21(8):816-822.
Authors:Jia-qi ZHANG  Guo-hua LIU  Jian-an HUANG
Institution:1. Department of Respiratory and Critical Care Medicine[East-section], Affliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China;2. Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Suzhou University, Suzhou 215031, China
Abstract:Since the emergence of the SARS-CoV-2 Omicron variant in November 2021, it has rapidly swept the world in a few months. Many countries in the world have witnessed a new round of epidemics with Omicron as the main epidemic strain, and some cities in China, such as Hong Kong, Shenzhen and Shanghai, have not been spared. Omicron spike protein contains a large number of mutations and has strong immune escape ability, which poses a great threat to the existing vaccines and antibody-related therapy. Although disease symptoms caused by Omicron variant are mild, the global health system is under great pressure due to its high transmission rate. In this paper, the pathogenic characteristics, variation sources, transmission characteristics, epidemic status and control measures of Omicron variant are reviewed, so as to provide reference for scientific control.
Keywords:SARS-CoV-2  Omicron variant  coronavirus disease 2019  prevention and control
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