体外受精-胚胎移植(IVF-ET)后临床妊娠随访报告

目的 探访接受IVF-ET治疗后临床妊娠患者不同妊娠胎数的妊娠结局。方法 1999年7月至2001年10月来我院生殖中心接受IVF-ET治疗后获得临床妊娠的患者259例，使用电话等方式进行随访，监测其妊娠状况直至分娩。比较单胎与多胎妊娠的妊娠结局及围产期情况。结果 单胎妊娠184例，流产23例，流产率12．5％，双胎妊娠62例，流产18例，其中2胎流产1胎9例，流产率29．0％，三胎妊娠13例，流产5例，其中3胎流产1胎3例，3胎流产2胎1例，流产率38．5％。单胎妊娠早期流产率11.4％，晚期流产率1.1％。单胎妊娠早产率2．7％，剖宫产率13．5％，围产儿死亡率0.6％；多胎妊娠平产率52.7％，剖宫产率70％，围产儿死亡率7．8％。结论 妊娠胎数与不良妊娠结局有相关性，随着妊娠胎数增加，流产以及部分胎儿丢失的风险随之增加；多胎妊娠早产率、剖宫产率及围产儿死亡率明显高于单胎妊娠。

The clinical pregnancy follow- up of in vitro fertilization and embryo transfer (IVF- ET)

Objective:To explore the correlation between the numbers of fetus pregnant women conceived and abortion.Methods:216 cases clinical pregnant women from July,1999 to December,2001 were studied.They were all suffered with IVF-ET.We monitored their variance from pregnancy to delivery by telephone.Then summarized and analyzed the recorders of abortion.Results:23 cases of 184 cases(23/184,12.5%)that are single pregnancy become abortive.There are 62 cases twin pregnancy,3 cases lost one fetus,and 1 case lost two fetuses. The total abortive rate 29.0%.In 13 cases triplet pregnancies,3 cases lost one fetus,1 cases lost two fetus.Conclusions:There are associations between the numbers of fetus and side outcome of pregnancy.The more fetus pregnant women conceived the more risk become abortive or lost part fetus and premature deliveries.