耐甲氧西林金黄色葡萄球菌的感染和治疗

作者分析了２４３例全身和局部的耐甲氧西林金黄色葡萄球菌（ＭＲＳＡ）感染情况。结果表明，本组ＭＲＳＡ占同期金黄色葡萄球菌感染的８０．５％。其中血液中分离的ＭＲＳＡ比例可高达９５．２％。多数ＭＲＳＡ对常用的第一、三代头孢类抗生素和某些新型喳诺酮类抗菌药物耐药，仅对万古霉素敏感。全身性ＭＲＳＡ感染仍以万古霉素最为有效。溶葡萄球菌酶作为外用药能有效地控制局部ＭＲＳＡ感染。

Methicillin resistant Staphylococcus aureus infection and its treatment

Local and systemic infections caused by Methicillin-resistant Staphylococcus aureus(MRSA)were analysed in 243 patients.Results showed that the incidence of MRSA isolated in this group was 80.5%(243 /302).59 out of 62 patients with systemic infection of MRSA. the isolated MRSA were most resistant to cephalosporins and sensitive to vancomycin which is most effective in treating systemic infec- tion of Staphylococuus aureus were MRSA infection. The isolated M RSA were most resistant to cephalosporins and sensitive to vancomycin which is most effective in treating systemic infection of MRSA. In order to control local MRSA infection,lysostaphin which is active against these organisrns could be used as a topical antimicrobial.