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| 卡介苗(BCG)多克隆抗体的免疫组化染色技术在麻风菌检测中的应用(附120例麻风病检测报告) | |
| 引用本文： | 刁镒兴,潘慧清,何桥,马瑞琼,黄进梅. 卡介苗(BCG)多克隆抗体的免疫组化染色技术在麻风菌检测中的应用(附120例麻风病检测报告)[J]. 岭南皮肤性病科杂志, 2005, 12(2): 105-106,116 |
| 作者姓名： | 刁镒兴 潘慧清 何桥 马瑞琼 黄进梅 |
| 作者单位： | 1. 广东省皮肤性病防治中心,广东,广州,510500 2. 广东省广州市胸科医院,广东,广州,510000 3. 广东省广州市皮肤病防治所,广东,广州,510000 |
| 摘 要： | 目的：讨论卡介苗(BCG)多克隆抗体对麻风病的早期诊断，治疗效果评估和复发病人发现的作用。方法：收集120例完成MDT、复发、少菌麻风病例。采用免疫组化技术BCG多克隆抗体检测标本组织中麻风杆菌抗原并与10％高碘酸氧化后做抗酸染色和一般抗酸染色做对比。结果：BCG组阳性率比10％高碘酸氧化后抗酸染色和一般抗酸染色高。结论：BCG多克隆抗体免疫组化染色对麻风病的早期诊断、治疗效果评估、复发的及时发现是一项操作简单而且敏感性高，是较有价值的检测项目。 |
| 关 键 词： | 麻风病 皮肤组织 BCG多克隆抗体 免疫组化 氧化 |
| 文章编号： | 1009-8968(2005)02-0105-03 |
| 修稿时间： | 2005-03-01 |
The Role of BCG Polyclonal Antibody in Leprosy Test--A Report of 120 Cases with Leprosy |
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| DIAO Jian-xing,PAN Hui-qing,HE Qiao,MA Rui-qiong,HUANG Jin-mei. The Role of BCG Polyclonal Antibody in Leprosy Test--A Report of 120 Cases with Leprosy[J]. Southern China Journal of Dermato-Venereology, 2005, 12(2): 105-106,116 | |
| Authors: | DIAO Jian-xing PAN Hui-qing HE Qiao MA Rui-qiong HUANG Jin-mei |
| Abstract: | Objective:To explore the role of BCG polyclonal antibody for early diagnosis of leprosy, assessment of therapeutic efficacy, and detection of the recurrent cases. Methods:120 cases of full course of treatment, recurrent and with little germ were collected, and BCG polyclonal antigen of them were tested by immunohistochemistry technology-leprosy polyclonal antibody test compared to coloration by 1% periodate and coloration by common antacid. Results:The positive rate of BCG group was higher than 10% periodate group and the common antacid coloration group. Conclusion:The test of BCG polyclonal antibody was better than coloration of antacid, therefore it is a simple, high sensitivity and with high value test for early leprosy diagnoses, assessment of therapeutic efficacy and promptly detection of the recurrent case. |
| Keywords: | leprosy tissue of skin BCG polyclonal antibody immunohistochemistry oxidation |
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