Numerical simulation of the influence of a left ventricular assist device on the cardiovascular system |
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Authors: | Verkerke G J Geertsema A A Mihaylov D Blanksma P K Rakhorst G |
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Institution: | Department of Biomedical Engineering, Faculty of Medical Sciences, University of Groningen, The Netherlands. G.J.Verkerke@med.rug.nl |
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Abstract: | The PUCA (pulsatile catheter) pump is a left ventricular assist device (LVAD) capable of unloading the left ventricle (LV) and improving coronary flow by providing a counterpulsation effect. It consists of an extracorporeal located membrane pump, coupled to a transarterial catheter that enters the body via a superficial artery and ends in the LV. Blood is aspirated from the LV and pumped in the ascending aorta through the same catheter guided by a valve system. Timing and frequency of the PUCA pump influence its efficacy. To study the influence of several pump parameters a numerical model of the device and the circulatory system has been developed. Results of animal experiments were used to validate the model. Optimization studies resulted in a pump configuration with a stroke volume of 50 cc and pump:heart frequency mode of 1:2 that starts ejection at the beginning of diastole. |
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