| 血清胃泌素诊断结直肠肿瘤的价值 |
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| 引用本文： | 张国全, 傅丽娜.血清胃泌素诊断结直肠肿瘤的价值[J].世界华人消化杂志,1997,5(3):178-179. |
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| 作者姓名： | 张国全 傅丽娜 |
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| 作者单位： | 250021,山东省济南市,山东省立医院腹部彩超室. |
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| 摘 要： | 目的研究结直肠肿瘤患者血清胃泌素水平与病情的相关性．方法经纤维结肠镜下活组织病理检查和／或术后病理确诊的结直肠腺瘤２８例和结直肠癌患者４６例，在排除有可能影响血清胃泌素水平的其它情况后，用ＲＩＡ法检测空腹血清胃泌素及ＣＥＡ含量．结果以胃泌素≥１００ｎｇ／Ｌ作为结直肠腺瘤的诊断指标，其敏感性、特异性和诊断效率分别为７５％，８１％和７８９％，以胃泌素≥１３０ｎｇ／Ｌ作为结直肠癌的诊断指标，其敏感性、特异性和诊断效率分别为７００％，９１９％和７９３％；而ＣＥＡ≥１５μｇ／Ｌ，则分别为３２０％，９４４％和４８５％．以胃泌素≥１３０ｎｇ／Ｌ作为癌肿与腺瘤的鉴别诊断指标，其敏感性、特异性和诊断效率都是７００％；而ＣＥＡ≥１５μｇ／Ｌ，则分别为３００％，９００％和４８６％．在早期结直肠癌患者，胃泌素≥１００ｎｇ／Ｌ者占７７８％，明显高于便血率（４５５％）．结论血清胃泌素对结直肠肿瘤的诊断和鉴别诊断优于ＣＥＡ，可作为结直肠癌的普查手段．
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| 关 键 词： | 结肠直肠肿瘤／血液 腺瘤／血液 胃泌素类／血液 |
Diagnostic value of serum gastrin in patients with colorectal neoplasms |
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| ZHANG Guo,Quan and FU Li,Na.Diagnostic value of serum gastrin in patients with colorectal neoplasms[J].World Chinese Journal of Digestology,1997,5(3):178-179. |
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| Authors: | ZHANG Guo Quan and FU Li Na |
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| Institution: | ZHANG Guo Quan and FU Li Na Department of Color sonodiagnostics,Shandong Provincial Hospital,Jinan 250021,Shandong Province,China |
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| Abstract: | AIM To study the diagnostic value of serum gastrin in patients with colorectal neoplasms. METHODS By using radioimmunoassay, the levels of serum gastrin (GAS) and carcinoembryonic antigen (CEA) were measured simultaneously in patients with colorectal cancer ( n =46) and colorectal adenoma ( n =28) diagnosed pathologically. The other circumstances possibly affecting the levels of serum gastrin were excluded. |
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| Keywords: | Colorectal neoplasms/blood Adenoma/blood Gastrins/blood |
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