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吸烟对男性精液质量、血睾酮水平及精浆左卡尼汀水平影响的研究
引用本文:刘嫱,房磊臣,苟欣,黄元华.吸烟对男性精液质量、血睾酮水平及精浆左卡尼汀水平影响的研究[J].重庆医科大学学报,2007,32(6):640-642.
作者姓名:刘嫱  房磊臣  苟欣  黄元华
作者单位:1. 重庆医科大学药学院药物化学教研室
2. 重庆医科大学附属第一医院泌尿外科,重庆,400016;海南医学院附属医院海南省生殖医学中心,海口,570102
3. 重庆医科大学附属第一医院泌尿外科,重庆,400016
4. 海南医学院附属医院海南省生殖医学中心,海口,570102
摘    要:目的:研究吸烟对男性精液质量、睾酮水平及精浆左卡尼汀水平的影响.方法:对有致孕史的男性,根据吸烟量和烟龄分为A、B、C 3组,检测精液参数(精液量、精子密度、精子前向运动百分率)、睾酮水平及精浆左卡尼汀水平.结果:精子密度、精子前向运动百分率A、C两组间有显著性差异;精子前向运动率B、C两组间有显著性差异;睾酮水平A、B组无明显差异,A、C组有显著性差异;左卡尼汀水平A、B两组间有显著性差异,A、C两组间差异非常显著(P<0.01).结论:长期大量吸烟可抑制睾丸的睾酮合成、降低精浆左卡尼汀水平,对精液参数、睾酮合成及精浆生化条件有不良影响,吸烟量越大、时间越长,影响越明显.

关 键 词:吸烟  精液质量  睾酮  左卡尼汀
文章编号:0253-3626(2007)06-0640-03
修稿时间:03 7 2007 12:00AM

Effect of smoking on semen quality, serum testosterone and level of L-carnitine in seminal plasma
LIU Qiang,et al.Effect of smoking on semen quality, serum testosterone and level of L-carnitine in seminal plasma[J].Journal of Chongqing Medical University,2007,32(6):640-642.
Authors:LIU Qiang  
Institution:Department of Pharmacochemistry , Pharmacy School, Chongqing Medical University
Abstract:Objective:To study the effect of smoking on the semen quality,the level of serum testosterone and L-carnitine in seminal plasma.Methods:90 men,who had the history of pregnancy individual,were divided into three groups.Semen parameters(volume,sperm density,viability,motility),serum testosterone and L-carnitine were examined.Results:There are significant difference between A and C group about sperm density and the percentage of progressive motile spermatozoa,and between B and C group about motility,and between A and C about serum testosterone,and between A and B about the level of L-carnitine,especilly between A and C group(P<0.01).Conclusion:Heavy and long-term smoking repress the synthesis of testosterone and decrease the level of L-carnitine in seminal plasma.Cigarette smoking appears to affect seminal parameter,serum testosterone and condition of seminal plasma.Heavier and longer would be more.
Keywords:Cigarette smoking  Semen quality  Testosterone  L-carnitine
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