| 阴茎血管活性物质及其功能递质在勃起功能障碍发病中的作用 |
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| 引用本文： | 李三祥,戴玉田. 阴茎血管活性物质及其功能递质在勃起功能障碍发病中的作用[J]. 中华男科学杂志, 2005, 11(11): 843-846 |
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| 作者姓名： | 李三祥 戴玉田 |
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| 作者单位： | 南京大学医学院附属鼓楼医院泌尿外科,江苏,南京,210008 |
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| 基金项目： | 江苏省“135工程”研究基金资助(RC2001002) |
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| 摘 要： | 阴茎海绵体是一种特殊的血管结构,勃起功能障碍(ED)的发病常与调节阴茎海绵体各种血管活性物质及其功能递质密切相关。调节阴茎血管的活性物质及功能递质,如血管紧张素和激肽、前列腺素类、内皮素、内皮源性超极化因子、一氧化氮合酶及一氧化氮、Rho激酶等在ED的发生中发挥重要作用,通过对这些活性物质及其功能递质的深入研究,可为ED治疗提供理论基础。
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| 关 键 词： | 勃起功能障碍 血管活性物质 阴茎 |
| 文章编号： | 1009-3591（2005）11-0843-04 |
| 收稿时间： | 2004-07-30 |
| 修稿时间： | 2004-12-04 |
Effects of Penile Vasoactive Mediators on the Development of Erectile Dysfunction |
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| LI San-xiang,DAI Yu-tian. Effects of Penile Vasoactive Mediators on the Development of Erectile Dysfunction[J]. National journal of andrology, 2005, 11(11): 843-846 |
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| Authors: | LI San-xiang DAI Yu-tian |
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| Affiliation: | Department of Urology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical College, Nanjing, Jiangsu 210008, China |
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| Abstract: | Penile corpus cavernosum can be seen as a special kind of vascular structure.The cause of erectile dysfunction(ED) is often related to the changes of penile vasoactive mediators which modulate the functional conditions of penile erectile tissues.The penile vasoactive mediators including angiotensin and kinins,prostaglandins,endothelins,endothelium-derived hyperpolarizing factors((EDHF)),NOS and NO,RhoA/Rho-kinases,etc.,may play an important role in the development of ED.Further researches on these mediators can furnish some theoretical evidence for the clinical treatment of ED. Natl J Androl,2005,11(11):843-846 |
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| Keywords: | erectile dysfunction vasoactive mediators penis |
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