功能残气量和残气容积测算及其临床意义

应用氦平衡法（Ｈｅ）法、氮冲洗法（ＷＯ法）和一口气氮稀释法（ＣＶ法）测定９６名健康人和１８０例不同肺胸疾病患者的功能残气量（ＦＲＣ），并计算出残气量／肺总量％（ＲＶ／ＴＬＣ％）。结果表明：健康组中，由Ｈｅ法和ＷＯ法测算的ＦＲＣ，男女间均有显著差异，用ＣＶ法测算的ＲＶ／ＴＬＣ％值亦非常显著高于Ｈｅ和ＷＯ法的测算值（Ｐ〈０．０１）。疾病组中，慢性支气管炎，肺气肿组的ＲＶ／ＴＬＣ％和ＦＲＣ／ＰＶ％明显升

The determination of FRC and RV and their clinical significance

The values of FRC and RV/TLC% in 96 healthy subjects and 180 cases of different lung and chest disorders were measured by the following three methods: helium equilibration method(He method) , nitrogen washout (WO method) and a single breath nitrogen test(CV method). The results showed that the FRC by He or WO method in men were markedly higher than that in women(P<0.01) in the healthy group. The values of RV/TLC% calculated by CV method were markedly higher than that by He and WO method. The equations of multiple regression of FRC were deduced. The values of RV/TLC% and FRC/ PV% in the groups of chronic bronchitis and lung emphysema were significantly higher than that in the groups of asthma , pleural effusion and thoracic deformity (P<0.01). Although there were no significant differences of the values between the asthma group and the pleural effusion group and thoracic deformity group , the FRC/PV% in the asthma group was also higher than that in the latter two groups. The results suggest that the determination of FRC and RV/TLC% may have a clinical significance to differentiate obstructive and restrictive disorders.