Simultaneous Delivery of Chemotherapeutic and Thermal-Optical Agents to Cancer Cells by a Polymeric (PLGA) Nanocarrier: An In Vitro Study |
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Authors: | Tang Yuan Lei Tingjun Manchanda Romila Nagesetti Abhignyan Fernandez-Fernandez Alicia Srinivasan Supriya McGoron Anthony J. |
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Affiliation: | (1) Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, Miami, Florida 33174, USA; |
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Abstract: | Purpose To test the effectiveness of a dual–agent-loaded PLGA nanoparticulate drug delivery system containing doxorubicin (DOX) and indocyanine green (ICG) in a DOX-sensitive cell line and two resistant cell lines that have different resistance mechanisms. |
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