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Simultaneous Delivery of Chemotherapeutic and Thermal-Optical Agents to Cancer Cells by a Polymeric (PLGA) Nanocarrier: An In Vitro Study
Authors:Tang  Yuan  Lei  Tingjun  Manchanda  Romila  Nagesetti  Abhignyan  Fernandez-Fernandez  Alicia  Srinivasan  Supriya  McGoron  Anthony J.
Affiliation:(1) Department of Biomedical Engineering, Florida International University, 10555 West Flagler Street, Miami, Florida 33174, USA;
Abstract:

Purpose  

To test the effectiveness of a dual–agent-loaded PLGA nanoparticulate drug delivery system containing doxorubicin (DOX) and indocyanine green (ICG) in a DOX-sensitive cell line and two resistant cell lines that have different resistance mechanisms.
Keywords:
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