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正交试验法优选烧伤膏中醇提部分的提取工艺
引用本文:康军民,任卫琼.正交试验法优选烧伤膏中醇提部分的提取工艺[J].中国药业,2009,18(15):31-32.
作者姓名:康军民  任卫琼
作者单位:1. 湖南省湘潭市韶山医院,湖南,湘潭,411105
2. 湖南中医药大学第一附属医院,湖南,长沙,410007
摘    要:目的考察烧伤膏中醇提部分的提取工艺。方法采用正交试验设计法,以浸膏得率、大黄素转移率为考察指标,优选提取工艺条件。结果提取因素按影响大小依次是乙醇浓度(A)〉乙醇量(B)〉回流时间(C),最佳提取条件是以85%乙醇为溶剂,加热回流提取2次,加醇量分别为药材量的8倍和6倍,提取时间分别为2h和1.5h。结论优化出的醇提部分的最佳提取工艺合理可行。

关 键 词:烧伤膏  浸膏得率  大黄素  正交试验  提取工艺

Optimized Extracting Technology of Ethanol Extracting Ingredients from Burns Ointment by Orthogohal Test Design
Kang Junmin,Ren Weiqiong.Optimized Extracting Technology of Ethanol Extracting Ingredients from Burns Ointment by Orthogohal Test Design[J].China Pharmaceuticals,2009,18(15):31-32.
Authors:Kang Junmin  Ren Weiqiong
Institution:1. Shaoshan Hospital of Xiaagtan City, Xiangtan, Hunan, China 411105; 2. First Affiliated Hospital, Hunan University of TCM, Changsha, Hunan, China 410007)
Abstract:Objective To observe the extracting technology of the ethanol extracting ingredients from Burns Ointment. Methods Using theemodin shift rate and extracting rate as indexes, the optimum extracting condition were optimized by orthogonal test design. Results The order of influencing factors for extraction was the concentration of ethanol(A) added ethanol volume(B) extracted times(C). The optimal extracting condition was 85% ethanol as solvent, reflux extracting twice, adding ethanol with 8 times and 6 times amount of medicinal materials, extracting time 2 h, 1. 5 h respectively. Conclusion The optimal extracting technology for ethanol extracting ingredients from Burns Ointment is reasonable and feasible.
Keywords:Burns Ointment  extracting rate  emodin  orthogonal test  extracting technology
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