静脉溶栓救治急性心肌梗塞的效果研究

目的:研究在急性心肌梗塞患者使用溶栓疗法来降低其死亡率与并发症。方法:27例急性心肌梗塞在首次症状发作12小时内,采用静滴日产尿激酶150万U(30分钟)。其疗效与采用常规治疗方案的27 例急性心肌梗塞作比较。结果:78％(21/27)经溶栓冶疗的患者呈现再灌注成功,2例(7%)并发严重心衰,对照者为8例(30%):5周后的死亡率冶疗组为7%,对照组为30%(P<0.01)。结论:在急性心肌梗塞病人采用静脉溶栓疗效可有效地降低死亡率与并发症。

A Clinical Study of Effect on Thrombolysis with Intravenous Uroknase in Acute Myocardial Infarction

Objectives: To study reduction mortality and complications after thrombolysis in acute myocardial infarction (AMI) .Methods:27 patients with AMI received urokinase (trade in Japan) 1 500 000 u with intravenous infusion within 30 minute for throtnbloysis from november 1994 through August 1998. UK infusion was at < 12 hour after the onset of the first symptoms, and comparison with 27 patients of contrast group with AMI received conventional therapy. Results: 21 Patients were successful reperfuson and 6 failured after thromboly-sis, the ratio of reperfusion was 78% . severe heart faiure occurred 8 patients (30%) in the contrast group, and 2 patients (7% ) in the thrombloysis. The five week mortality in ptient with contrast group was 8 (30% ) versus 2(7% ) in thrombolysis group ( P < 0.01 ). Conclusions: Intravenous thrombolysis in acute myocardial infarction has affirmative effect for reduction mortality and Complications.