儿童期接受双侧斜疝手术所致梗阻性无精子症的临床特征及治疗策略

儿童期斜疝手术是输精管梗阻的常见原因之一。输精管输精管吻合术可重建输精管道，使部分患者精液中可检出精子并自然受孕。与输精管结扎术后吻合术不同的是，斜疝术后输精管长期不通畅可导致继发性附睾梗阻。自2007年7月至2012年6月，共有62名幼时有双侧斜疝手术史的梗阻性无精子症患者在我中心接受治疗。总体再通率和自然妊娠率分别为56．5％（35／62）和25．8％（16／62）。48．4％（30／62）的患者接受腹股沟区的双侧VV吻合术，再通率和自然妊娠率分别为76．7％（23／30）和36．7％（11／30）。30．6％的患者由于附睾梗阻接受双侧VV吻合术和单／双侧输精管附睾显微吻合术，再通率和自然妊娠率分别降至63．2％（12／19）和26．3％（5／19）。21．O％（13／62）由于未查见输精管远侧断端仅接受精道探查术。我们的研究认为精道显微吻合是治疗儿童期斜疝手术所致梗阻性无精子症的有效方法。

Clinical features and therapeutic strategies of obstructive azoospermia in patients treated by bilateral inguinal hernia repair in childhood

Childhood inguinal herniorrhaphy is one common cause of seminal tract obstruction. Vasovasostomy （VV） can reconstruct seminal deferens and result in appearance of sperm and natural pregnancy in some patients. Secondary epididymal obstruction caused by a relatively long-term vasal obstruction is a common cause of lower patency compared with VV due to vasectomy in adults. From July 2007 to June 2012, a total of 62 patients, with history of childhood inguinal herniorrhaphy and diagnosed as obstructive azoospermia were treated in our center. The overall patency rate and natural pregnancy rate were 56.5% （35/62） and 25.8% （16/62）, respectively. 48.4% （30/62） of the patients underwent bilateral VV in the inguinal region, with a patency rate of 76.7% （23/30） and a natural pregnancy rate of 36.7% （11/30）, respectively. 30.6% （19/62） of the patients underwent bilateral VV and unilateral or bilateral vasoepididymostomies due to ipsilateral epididymal obstruction with the patency and natural pregnancy rate decreasing to 63.2% （12/19） and 26.3% （5/19）. 21.0% （13/62） of the patients merely underwent vasal exploration without reconstruction due to failure to find distal vasal stump, etc. Our study indicate that microsurgical reanastomosis is an effective treatment for some patients with seminal tract obstruction caused by childhood inguinal herniorrhaphy.