The effect of higher nervous activity disturbance on hemoglobin metabolism

Summary The effect of higher nervous activity disturbances on hemogiobin metabolism in the dog was studied. The disturbances were caused by the combination of food and defense unconditioned reflexes and by a combination of inhibitory and excitatory processes, after a conditioned defense electric skin reflex and its differentiation had been previously formed. It was discovered that after the development of the neurotic state caused by such disturbances, hemoglobin decomposition in animals was intensifled. Due to the compensatory augmented erythrocyte formation, the hemoglobin level of the blood did not materially change at the beginning, but with the progressive aggravation of the neurotic state, compensation failed and the hemoglobin level considerably decreased.Presented by Academician G. N. Speransky