肺韦格纳肉芽肿病CT征象分析

目的：探讨肺韦格纳肉芽肿痛的临床及CT表现，进一步提高对该病的认识及诊断水平。方法：回顾分析经病理证实的11例肺韦格纳肉芽肿痛的临床及影像学资料，总结其临床及影像学特点。结果：儿例患者中，多发肿块、结节影10例（91％），伴空洞形成8例，病灶周围毛刺征3例，胸膜凹陷征1例，晕征4例，血管供给征6例。浸润性阴影4例（36％），其中3例伴多发结节及空洞形成。气道受累3例（27％），胸膜受累2例（18％）。抗中性粒细胞胞质抗体（c—ANCA）阳性10例，cANCA阴性1例。结论：多发病灶周围的毛刺征、晕征以及伴发的气道改变对韦格纳肉芽肿病的鉴别诊断具有重要意义。

Analysis of CT features of Pulmonary Wegenegs Granulomatosis

Objective： To explore the clinical, CT and PET/CT features of pulmonary Wegener＇s granulomatosis （WG） in order to further improve its diagnostic accuracy. Methods：Clinical and imaging characteristics of 11 patients with WG proved by pathology were retrospectively analyzed. CT scans were performed for all the 11 patients before treatment. Results： The main CT features of WG were multiple pulmonary nodules or masses （10 of 11 cases, 91 % ）, pulmonary nodules with cavitations （8 of 11 cases, 72 % ）. Spiculation （3 of 11 cases, 27 % ）, pleural indentation（ 1 of 11 cases, 9 % ） , halo sign （4 of 11 cases, 36 % ）, and feeding vessel sign （6 of 11 cases, 55 % ） were found around the nodules or masses. Ground-Glass O- pacity or consolidation （4 of 11 cases,36%） ,airway involvement （3 of 11 eases,27%） and pleural involvement （2 of 11 ca-ses, 18 %） were also detected. Ten patients were c-ANCA positive and one was negative. Conclusion： Multiplicity of the le-sions with ＂spiculation＂, ＂halo sign＂ as well as the accompanied changes of airway may play an important role in differential diagnosis of WG.