| 血清肌钙蛋白I对儿童病毒性心肌炎的诊断价值 |
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| 引用本文： | 王建华,张淑英,徐晋丹,卞智萍. 血清肌钙蛋白I对儿童病毒性心肌炎的诊断价值[J]. 江苏医药, 2000, 26(8): 586-587 |
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| 作者姓名： | 王建华 张淑英 徐晋丹 卞智萍 |
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| 作者单位： | 1. 210029,南京医科大学第一附属医院儿科
2. 210029,南京医科大学第一附属医院心血管研究所 |
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| 摘 要： | 目的了解心肌特异性肌钙蛋白Ⅰ（ｃＴｎＩ）对病毒性心肌炎的诊断价值。方法用双抗ＥＬＩＳＡ法动态测定４６例病毒性心肌炎患的血清ｃＴｎＩ，同时检测肌酸激酶同功酶（ＣＫ－ＭＢ）。结果４６例患ｃＴｎＩ的阳性率为８０．４％，ＣＫ－ＭＢ的阳性率为４５．７％（Ｐ〈０．０５）。病程１５天ｃＴｎＩ的检出率为８０．４％，而ＣＫ－ＭＢ的检出率为２１．３％（Ｐ〈０．０１）。病程６０天ｃＴｎＩ的检出率为２４．４％，而ＣＫ
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| 关 键 词： | 病毒性心肌炎 心肌特异肌钙蛋白Ⅰ 诊断 儿童 |
Diagnostic value of serum troponin I in children with viral myocarditis |
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| WANG Jianhua,ZHANG Shuyin,XU Jindan,et al.. Diagnostic value of serum troponin I in children with viral myocarditis[J]. Jiangsu Medical Journal, 2000, 26(8): 586-587 |
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| Authors: | WANG Jianhua ZHANG Shuyin XU Jindan et al. |
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| Affiliation: | WANG Jianhua,ZHANG Shuyin,XU Jindan,et al. Department of Pediatrics,the First Affiliated Hospital,Nanjing Medical University,Nanjing 210029 |
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| Abstract: | Objective To evaluate the diagnostic value of cardiac troponin I(cTnI) in myocardial injury of viral myocarditis(VMC).Methods Serum levels of cTnI was assayed with a double monoclonal ELISA.Concentration of isoenyme of creatine kinase(CK-MB) was measured at the same time.Results In 46 patients with VMC,the positive detection rate of cTnI was 80 4%,and that of CK-MB was only 45 7%( P <0 05).At the fifteenth day,the positive detection rate of cTnI was 80 4%,but that of CK-MB was only 21 3%( P <0 01).At the sixtieth day,the positive detection rate of cTnI was 24 4% and that of CK-MB was normal.Conclusion The sensitivity and specificity of the serum cTnI to diagonse VMC are excellent,and the assay window time of cTnI is also longer than that of CK-MB.The assay of cTnI might become a good index in the early diagonsis of VMC and the determin ation of its progress. |
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| Keywords: | Children Viral myocarditis Troponin I |
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