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Embryology of the craniocervical junction and posterior cranial fossa,part II: Embryogenesis of the hindbrain
Authors:Mohammadali M. Shoja  Rebecca Ramdhan  Chad J. Jensen  Joshua J. Chern  W. Jerry Oakes  R. Shane Tubbs
Affiliation:1. Neuroscience Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;2. Department of Anatomical Sciences, St. George's University School of Medicine, Grenada;3. Seattle Science Foundation, Seattle, Washington;4. Children's Hospital of Alabama, Birmingham, Alabama
Abstract:Although pathology of the hindbrain and its derivatives can have life altering effects on a patient, a comprehensive review on its embryology is difficult to find in the peer‐reviewed medical literature. Therefore, this review article, using standard search engines, seemed timely. The embryology of the hindbrain is complex and relies on a unique timing of various neurovascular and bony elements. Derailment of these developmental processes can lead to a wide range of malformations such as the Chiari malformations. Therefore, a good working knowledge of this embryology as outlined in this review of the hindbrain is important for those treating patients with involvement of this region of the central nervous system. Clin. Anat. 31:488–500, 2018. © 2018 Wiley Periodicals, Inc.
Keywords:genetics  anatomy  malformation  Chiari  brain, nervous system  cerebellum  brain stem
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