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Hexane fraction of Zingiberis Rhizoma Crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway
Authors:Hyo Won Jung  Cheol-Ho Yoon  Kwon Moo Park  Hyung Soo Han  Yong-Ki Park
Institution:1. Department of Herbology, College of Oriental Medicine, Dongguk University, Seok-Jang Dong, Gyeongju 780-714, Republic of Korea;2. Department of Internal Medicine, College of Oriental Medicine, Dongguk University, Gyeongju 780-714, Republic of Korea;3. Department of Anatomy, School of Medicine, Cell and Matrix Research Institute Stroke Center, Kyungpook National University Hospital, Daegu 700-422, Republic of Korea;4. Brain Science and Engineering Institute, Cell and Matrix Research Institute Stroke Center, Kyungpook National University Hospital, Daegu 700-422, Republic of Korea
Abstract:
Keywords:GHE  ginger hexan extract  iNOS  inducible nitric oxide synthase  IL  interleukin  LPS  lipopolysacchride  MAPK  mitogen-activated protein kinase  NF-κB  nuclear factor-kappaB  NO  nitric oxide  TNF  tumor necrosis factor
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