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Protective effect of quince (Cydonia oblonga Miller) fruit against oxidative hemolysis of human erythrocytes
Authors:Ana S. Magalhã  es,Branca M. Silva,José   A. Pereira,Paula B. Andrade,Patrí  cia Valentã  o,Má  rcia Carvalho
Affiliation:1. CEBIMED, Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, R. Carlos da Maia, 296, 4200-150 Porto, Portugal;2. REQUIMTE, Serviço de Farmacognosia, Faculdade de Farmácia, Universidade do Porto, R. Aníbal Cunha, 4050-047 Porto, Portugal;3. CIMO, Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Apartado 1172, 5301-855 Bragança, Portugal;4. REQUIMTE, Serviço de Toxicologia, Faculdade de Farmácia, Universidade do Porto, R. Aníbal Cunha, 4050-047 Porto, Portugal
Abstract:The aim of this study was to determine the phenolic content and evaluate the antioxidant activity of quince (Cydonia oblonga) fruit. For this purpose, fruits were separated into pulps, peels and seeds and methanolic extracts were prepared. The phenolic profiles were determined by HPLC/UV and antioxidant properties were studied for their ability to quench the stable free radical 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and to inhibit the 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced oxidative hemolysis of human erythrocytes.
Keywords:Cydonia oblonga   Quince   Phenolic compounds   Erythrocyte   Antioxidant activity   Hemolysis
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