Gray matter morphology and the level of functioning in one-year follow-up of first-episode schizophrenia patients |
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| Authors: | Tomas Kasparek Radovan Prikryl Daniel Schwarz Hana Kucerova Radek Marecek Michal Mikl Jiri Vanicek Eva Ceskova |
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| Affiliation: | 1. Department of Psychiatry, Masaryk University, Faculty of Medicine and Faculty Hospital Brno-Bohunice, Brno, Czech Republic;2. Institute of Biostatistics and Analysis, Masaryk University, Faculty of Medicine, Brno, Czech Republic;3. Department of Neurology, Masaryk University, Faculty of Medicine and Faculty hospital St. Anna, Brno, Czech Republic;4. Department of Imaging Methods, Masaryk University, Faculty of Medicine and Faculty hospital St. Anna, Brno, Czech Republic |
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| Abstract: | Schizophrenia is a condition with a highly variable course that is hard to predict. The aim of the present study was to investigate if local gray matter volume (GMV) can differentiate poor (PF) and good (GF) functioning patients using voxel-wise analysis in a group of first-episode schizophrenia subjects (FES). |
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| Keywords: | DSM, Diagnostic and Statistical Manual of Mental Disorders FP, frontopolar FEW, Family Wise Errors FWHM, full width at half maximum GAF, Global Assessment of Functioning GF, good functioning HC, healthy controls ICBM, International Consortium for Brain Mapping ICD-10, International Statistical Classification of Disease and Related Health Problems MNI, Montreal Neurological Institute OFC, orbitofrontal cortex PANSS, Positive and Negative Syndrome Scale PF, poor functioning VBM, voxel-based morphometry |
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