神经外科肺部感染多重耐药菌调查分析与防控对策

目的研究医院神经外科住院患者肺部感染多重耐药菌特点,探讨有效防控对策。方法通过回顾性调查的方法,对某医院神经外科住院患者肺部感染的病原菌进行了分离鉴定与分析。结果从63例肺部感染患者标本中共分离出病原菌20种134株,包括革兰阴性杆菌82株、革兰阳性球菌33株以及真菌19株。82株革兰阴性杆菌中鲍曼不动杆菌、肺炎克雷伯菌和铜绿假单胞菌分居前三位,构成比分别为15.67%、13.43%和13.43%;革兰阳性球菌居首位的是金黄色葡萄球菌,占13.43%。所检出的病原菌多数呈多重耐药,同时耐受三种或三种以上抗菌药物。结论神经外科住院患者肺部感染以革兰阴性杆菌为主,多数呈多重耐药,以控制侵入性操作和消毒隔离为主要防控对策。

ANALYSIS AND PREVENTION STRATEGIES FOR MULTI-RESISTANT BACTERIA IN PATIENTS WITH PULMONARY INFECTION IN NEUROSURGERY DEPARTMENT

Objective To investigate the characteristics of multi-resistant bacteria in patients with pulmonary infection in neurosurgery department and to discuss effective prevention strategies.Methods The retrospective investigation was used to investigate the pathogenic bacteria infected in pulmonary of inpatients in neurosurgery department of this hospital.Results 134 strains of pathogenic bacteria with 20 species were isolated from 63 cases of pulmonary infection patients,which including 82 strains Gram-negative bacilli,33 strains Gram-positive coccus and 19 strains fungi.Within 82 strains of Gram-negative bacilli,the top three were Acinetobacter baumannii,Klebsiella pneumoniae and Pseudomonas aeruginosa and the ratios were 15.67%,13.43% and 13.43%,respectively.Staphylococcus aureus was the primary pathogenic bacteria in Gram-positive coccus,accounting for 13.43%.Most of the detected pathogenic bacteria were multi-resistant to three or more antibiotics.Conclusion Gram-negative bacteria is presented as the main pathogenic bacteria in hospitalized patients with pulmonary infection in neurosurgery department,and most of them are multi-resistance.So standardizing the invasive operation and implementation of disinfection and segregation are the two main prevention strategies.