住院患者尿路感染细菌耐药性调查

目的了解住院患者尿路感染细菌耐药情况,为临床用药提供参考。方法通过细菌分离培养和药敏试验方法,对某医院2010年7月-2011年12月期间住院尿路感染患者的尿液标本中分离的致病菌进行了调查与分析。结果在调查期间从住院尿路感染患者的尿液标本中分离出病原菌153株,其中革兰阴性菌占59.48%,居前3位的细菌是大肠埃希菌、肺炎克雷伯菌和铜绿假单胞菌。检出革兰阳性菌占22.88%,主要是肠道球菌。尿路感染的病原菌对多数抗菌药物耐药。结论尿路感染病原菌以革兰阴性菌为主,革兰阳性菌仍以肠道球菌为主,并且普遍耐药。

INVESTINGATION OF BACTERIAL DRUG RESISTANCE OF URINARY TRACT INFECTION PATIENT IN HOSPITAL

Objective To investigate the drug resistance of the bacteria leading to urinary tract infection in hospital,and provide the guidance for rational drug use in clinic.Method Bacterial seperation and cultivation and susceptibility test were used to investigate and analyze pathogenic bacterial isolated from clinical urinary samples which suffered urinary tract infection in hospital from July 2010 to December 2011.Results 153 strains of pathogenic bacteria were isolated from clinical urinary samples of urinary tract infection patients in hospital.The Gram-negative bacteria was the main pathogen,which accounting for 59.48%.The top three were Escherichia.coli,Klebsiella pneumoniae and Pseudomonas aeruginosa.And the main Gram-positive bacteria was Enterococcus,which accounting for 22.88%.The urinary tract infection pathogens resisted to most antimicrobial agents.Conclusion The Gram-negative bacteria is the main pathogenic bacteria of urinary tract infection patients in hospital,and the main Gram-positive bacteria is Enterococcus,which has general drug resistance.