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外科性黄疸和黄疸型病毒性肝炎患者血清SIgA的变化
引用本文:冯祖亮,王平,冯新为.外科性黄疸和黄疸型病毒性肝炎患者血清SIgA的变化[J].郧阳医学院学报,1994(4).
作者姓名:冯祖亮  王平  冯新为
作者单位:武汉市第四医院外科,同济医科大学免疫学教研室
摘    要:外科性黄疸(surgicaljaundice,SJ)患者(38例)术前血清分泌型IgA(scretoryIgA,SIgA)含量为140.8±51.3μg/ml,比正常人(30人)的平均值(8.9±2.1μg/ml)高15.8倍(P<0.01).手术解除胆道硬阻后15~20d,SJ患者的血清SIgA水平显著下降(P<0.01);同时,术后胆汁中的SigA却远高于术中时胆汁SIgA的水平(P<0.01)。黄疸型病毒性肝炎(ictericviralhepatitis,IVH)患者(30例)的血清SIgA含量也显著增多(76.4±27.8μg/ml,P<0.01),然而却远低于SJ患者的水平(P<0.05)。

关 键 词:黄疸/外科性,病毒性肝炎,免疫球蛋白A,分泌型

Changes in Serum SIgA Levels in Patients with Surgical Jaundice and Icteric Viral Hepatitis
Feng Zuliang,et al.Changes in Serum SIgA Levels in Patients with Surgical Jaundice and Icteric Viral Hepatitis[J].Journal of Yunyang Medical College,1994(4).
Authors:Feng Zuliang  
Abstract:The average preoperative serum SIgA level in 38 patients with surgical jaundice(SJ)was 140.8±51.3μg/ml,which was 15.8 times as high as the control value,the average serum SIgA value of 30 normal individuals (8.9±2.1μg/ml,P<0.01).Surgical relief of the bile duct obstruction in SJ patients resulted in a dramatic fall of the serum SIgA level 15~20 days after the operation (P<0.01), while the postoperative bile SIgA the operation (P<0.01), while the postoperative bile SIgA value rose to a much higer level than that before renewal of the bile flow(P<0.01).In 30 patients with icteric viral hepatitis,there was also a significant rise in the average serum SIgA level (76.4±27.8μg/ml,P<0.01),which was,however, much lower than in patients with SJ (P<0.05).
Keywords:aundice surgical hepatitis  viral IgA  secretory
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