高校职工糖尿病前期干预研究

目的探讨生活干预联合药物控制延缓糖尿病前期发展为糖尿病的程度。方法对2011年6月某高校体检确诊为糖尿病前期200例职工进行观察,随机分为干预组（生活干预＋药物控制）与对照组,观察期限为2年,比较两组患者1年后、2年后基础信息和糖尿病患病率。结果两组糖尿病前期职工干预前基础信息比较差异无统计学意义;观察组1年后糖尿病患病率为1%,对照组为13%,差异有统计学意义（χ^2=11.06,P〈0.01）;观察组2年后糖尿病患病率为2%,对照组为20%,差异有统计学意义（χ^2=11.06,P〈0.01）。结论生活干预联合药物控制可能延缓糖尿病前期发展为糖尿病。

An intervention study on the pre-diabetes of college employees

Objective To investigate the role of the pre-diabetes intervention of college employees to diabetes mellitus. Methods 200 cases of college employee with pre-diabetes diagnosed at June 2011 were observed, who were randomly allocated to an intervention group（living intervention ＋ pharmacological treatment） and a control group, which were observed for a period of two years. The basic information and diabetes prevalence after 1 year or 2 years in the two groups were compared. Results Differences of the basis information of employees with pre-diabetes between two groups were no statistically significant; one year later diabetes prevalence rate in the observation group was 1%, that in the control group was 13%, the difference was statistically significant（χ^2=11.06, P〈0.01）; two years later diabetes prevalence rate in the observation group was 2%, which in the control group was 20%, the difference was statistically significant（χ^2=11.06, P〈0.01）. Conclusion Living intervention and pharmacological treatment may delay the development of diabetes from pre-diabetes.