精氨酸对治疗性内镜逆行胰胆管造影后急性胰腺炎的预防作用

目的 :探讨精氨酸对治疗性内镜逆行胰胆管造影 (ERCP)后急性胰腺炎的预防作用。方法 :173例胰管均显影的患者随机分成治疗组 (A组 ,n =87)和对照组 (B组 ,n =86 ) ,A组治疗前、后静滴精氨酸 ,B组除不用精氨酸外 ,其他处理方法同A组。结果 :治疗性ERCP后高淀粉酶血症发生率 ,A组和B组分别为 2 7 6 %和 6 5 1% (P <0 0 1) ,急性胰腺炎发生率分别为2 3%和 11 6 % (P <0 0 5 )。结论 :精氨酸对治疗性ERCP后急性胰腺炎有明显的预防作用。

Effect of arginine preventing the acute pancreatitis after therapeutic endoscopic retrograde cholangiopancreatography

AIM: To investigate the effect of arginine preventing the acute pancreatitis after therapeutic endoscopic retrograde cholangiopancreatography (ERCP). METHODS: One hundred and seventy three cases whose acute pancreatic duct were developed were randomly assigned into 2 groups: 87 cases in study group (group A) and 86 cases in control group (group B). Arginine was used in group A before and after ERCP. The treatment was used in group B was the same as it was used in group A but the use of arginine. RESULTS: The rate of high amylase blood occuring was 27.6% and 65.1% in group A and group B respectively. The rate of acute pancreatitis occuring was 2.3% and 11.6% in group A and group B respectively. CONCLUSION: The effect of arginine preventing the acute pancreatitis after therapeutic ERCP is obvious.