盛京医院专项整治活动前后围手术期抗菌药物应用分析

目的：分析盛京医院抗菌药物专项整治活动前（未干预组）、后（干预组）Ⅰ类切口手术围手术期预防性应用抗菌药物（下文简称“预防用药”）情况，评价该专项整治活动的有效性。方法：以本院抗菌药物专项整治活动前后Ⅰ类切口手术病例为研究对象，通过筛查，入选未干预组（2011年10-11月）病例533例，干预组（2012年10-11月） 病例504例，从预防用药百分率、人均用药天数、给药时机合理性、抗菌药物种类、联合用药百分率等方面评价预防用药合理性。结果：未干预组预防用药百分率为62.29%，干预组降低为25.40% （P〈0.01）。未干预组预防用药人均天数为（2.03±0.96） d，干预组缩短为（1.68±1.57） d （P〈0.01）。干预组术前给药时机的合理率和术后用药持续时间的合理率均较未干预组显著增加（P〈0.01，P〈0.05）。结论：专项整治活动后，本院Ⅰ类切口手术围手术期预防用药情况有所改善，提示专项整治活动有效。

Analysis of antibacterials applications in the perioperative period in Shengjing Hospital before and after the special rectification activity

Objective： To evaluate the effectiveness of the special rectification activity by analyzing and comparing the prophylactic application of antibacterials in class I （clean） wounds during the perioperative period in Shengjing Hospital before and after the special rectification activity. Methods： Cases with class I wounds were chosen as the subjects of the study. There were 533 cases in the non intervention group （from Oct. 2011 to Nov. 2011） and 504 cases in the intervention group （from Oct. 2012 to Nov. 2012） chosen respectively before and after the special rectification activity. Such indicators as the percentage of prophylactic application of drugs, the duration of n, edication on the average, the rationality of medication time, types of anti bacterials and the percentage of drug combination were used to evaluate the rationality in the application of prophylactic drugs. Results： The percentage of the application of prophylactic drugs for the non-intervention group was 62.29%, while the percent age of the intervention group decreased to 25.40%（P〈0.01）. The duration of medication for the non-intervention group was （2.03 ± 0.96） days per case, while that for the intervention group decreased to （1.68 ± 1.57） days （P〈.0.01）. The ration- ality of medication time before and after surgery for the intervention group all significantly improved, when they were compared with those of the non intervention group （P〈0.01, P〈0.05）. Conclusion： After the special rectification activity, the rationali ty in the application of prophylactic antibacterials in class I wounds during the perioperative period was improved, indicating that the special rectification activity was effective.