两种指标计算住院病人抗菌药物使用强度的适用性比较

目的：比较采用实际占用总床日数和收治病人人数天数计算住院病人抗菌药物使用强度（antibacterial use density， AUD）的准确性，以确定一个适用性更高的AUD计算方法。方法：分别使用实际占用总床日数和收治病人人数天数（即抽样时间段内出院人数×平均住院天数）计算上海市公共卫生临床中心2009-2011年每年，以及2012年1-3月每月住院病人的AUD，记为AUD1和AUD2，比较月度AUD1和AUD2、年度AUD1和AUD2的离散度。结果：月度AUD1的离散度显著小于月度AUD2离散度，年度AUD1和年度AUD2的离散度相差不大。结论：与收治病人人数天数相比，使用实际占用总床日数计算AUD适用性更佳，更能真实反映住院病人抗菌药物使用水平。

Applicability comparison of two indexes for calculating the antibacterials use density

Objective： To acquire a more applicable way of calculating antibacterial use density（AUD） by comparing the accuracy of the practically occupied bed days with the number of discharged patients multiplied by the average hospitalization days. Methods： Monthly AUD from January 2012 to March 2012 and annual AUD from 2009 to 2011 of the inpatients of Shang hal Public Health Clinical Center were calculated by two indices, respectively. In detail, AUD2 was calculated by the occupied bed days, and AUD2 was calculated by the number of discharged patients multiplied by the average hospitalization days. The dispersion of AUD2 , both monthly and annual, were compared with that of AUD2, respectively. Results： The dispersion of the monthly AUD2 was significantly lower than that of the monthly AUD2, but there were no significant differences in the disper- sion of annual AUD, and the annual AUD2. Conclusion： The applicability of the practically occupied bed days is better than the numbers of discharged patients multiplied by the average hospitalization days in calculating the individual clinical AUD, which can truly reflect the AUD of inpatients.