106例新生儿败血症的细菌学分类及抗生素耐药性分析

目的：了解新生儿败血症病原菌及耐药性,为临床用药提供依据。方法：对106例新生儿血培养阳性标本进行细菌鉴定及药敏结果进行分析。结果：106例阳性标本中金黄色葡萄球菌和表皮葡萄球菌分别占42.5%和14.2%,对多种抗生素耐药,苯唑西林的耐药率分别为63.6%、88.6%,对万古霉素100%敏感;革兰阴性菌中大肠埃希菌占首位,其次为洛菲不动杆菌,抗菌活性较好的药物是阿米卡星、环丙沙星。结论：葡萄球菌是新生儿败血症的主要病原菌;临床医师应根据细菌鉴定及药敏试验选择敏感药物治疗。

Pathogens and Antibiotic Resistance of Isolates from Newborn Septicemia Blood Cultures

Objective： To understand the distribution of pathogens causing newborn septicemia and their antibiotic resistance. Methods： The samples positive in blood culture of newborn in our hospital were analyzed. Results： Among 106 positive in blood culture,positive ratio of Staphylococcus S. aureus and S. epidermidis were 42.5% and 14.2%, respectively. Furthermore, they were multiresistant. The ratio of meticillinresistant S. epidermidis and S. aureus were 63.6% and 88.6% ,respectively, but all were sensitive to vancomycin. Among grnmnegative bacteria, Escherichia coli was in the first place, the second one was Ainetobater lwoffi strains, The better antibiotics for them were amikacin, ciprofloxacin. Conclusion： Staphylococcus spp is one of the main pathogens causing newborn septicemia, The identification of bacteria and drug sensitive test were helpful to clinical therapy.