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城镇人群1194例HP尿素酶抗体测定对HP流行病学的研究
引用本文:李智,陈振侬.城镇人群1194例HP尿素酶抗体测定对HP流行病学的研究[J].临床消化病杂志,1993,5(2):49-51.
作者姓名:李智  陈振侬
作者单位:广西医科大学附属一院消化科,广西医科大学附属一院消化科,广西医科大学附属一院消化科 530027 研究生 桂林医学院工作,530027,530027
摘    要:以6株幽门螺杆菌(HP)尿素酶作为抗原,用间接酶联免疫法(ELISA)检测城镇人群1194例HP感染的流行病学调查。结果:该试验敏感性为90%,特异性为90%;HP感染率为40.2%,并随年龄增长而增加;有上消化道症状的HP感染率明显高于无症状者(P<0.05)。其感染率与性别、职业、地区分布、血型和个人烟酒嗜好无关。

关 键 词:幽门螺杆菌  流行病学  尿素酶  抗体

Seroepidemiological Study of Helicobacter Pylori in 1194 Cases of Cities and Towns Detecting Anti--urease Antibody
Li Zhi,Chen Zhen-nong,Hong Rui-Xiang.Seroepidemiological Study of Helicobacter Pylori in 1194 Cases of Cities and Towns Detecting Anti--urease Antibody[J].Chinese Journal of Clinical Gastroenterology,1993,5(2):49-51.
Authors:Li Zhi  Chen Zhen-nong  Hong Rui-Xiang
Institution:Li Zhi,Chen Zhen-nong,Hong Rui-Xiang Department of Digestive Disease,First Affiliated Hospital of Guangxi Medical University
Abstract:The urease extract of Helicobacter pylori (HP) was used as antigen to detect sera anti-urease antibodies of HP in 1194 cases of cities and towns by ELISA for the epidemiological study of HP infection. The results showed that sensitivity and specificity were 90% respectively, the HP infection rate was 40.2% and was increased with age and was higher (P<0.05) among persons with upper gastrointestinal symp- toms than without those symptoms. HP infection had no relation to sexes, occupation, blood types, regions, smoking and drinking.
Keywords:Hellcobacter pylori (HP)  Epidemiology  Anti-urease antibody
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