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HEPATECTOMY FOR PRIMARY LIVER CANCER JN114 CASES A FOLLOW-UP STUDY WITH LONG-TERM RESULTS
Authors:G C Li  C E Wang  S L Zhu  Z C Deng  G H Li  D S Wan  J Q Li  Y Q Zhan
Abstract:Between July 1955 and December 1980, 536 pathologically confirmed primary liver carcinoma cases underwent abdominal exploration at the Liver Cancer Research Unit, Zhongshan Medical College. Among them, 114 had various types of hepatectomy, with a 21.3To resectability rate and an operative mor tality of 11.4Tv. The l-, 3-, 5 and 10-year survival rates were 58.6To, 32.1'/o, 23.1To and 21.4'70. Of the 114 resections, 14 had small tumors measuring 5 cm or less in diameter. The survival rates in the group were 100%, 74.60'/o and 59.670 for l-, 3- and 5-year survivals. Six survived more than 10 years, five have been living and well for 11 years and 9 months, 13 years and 11 months, 16 years and 2 months, 17 years and 9 months, and 21 years and 10 months respectively after operation. All are able to work. One little girl with primary hepatocellular carcino- ma with a left hemi-hepatectomy and removal of a tumor weighing l.2 kilograms at age of 4 years and 7 months, is now a healthy young woman of 22 years and 4 months of age with normal development and normal working capacity. One patient died of recurrence of liver cancer and wide-spread metastases 1I years and one month after the operation. Factors influencing Iong-term results of hepatec tomies for primary liver cancer are analysed and discussed in the paper. From our 28 years of clinical experience, we be- lieve that the key to improving results of surgical treatment of primary liver cancer lies in early detec tion, early diagnosis, early and complete removal of the primary liver cancer and limitation of the resec tion to within 40% of total liver substance. Hepa- tectomy with resection exceeding 40% t0 5010 0f the liver in patients with primary liver carunoma asso ciated with moderate to severe cirrhosis usually re- sults in fatality.
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