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连续6年外科重症监护病房真菌感染的监测
引用本文:刘方,安友仲,武迎宏,李纾,张振宇,马丽,王占伟,冯双云. 连续6年外科重症监护病房真菌感染的监测[J]. 中华医院感染学杂志, 2009, 19(22)
作者姓名:刘方  安友仲  武迎宏  李纾  张振宇  马丽  王占伟  冯双云
作者单位:1. 北京大学人民医院外科重症监护病房,北京,100044
2. 北京大学人民医院院内感染科,北京,100044
3. 北京大学人民医院细菌室,北京,100044
基金项目:北京市医院管理质量控制及改进中心资助 
摘    要:目的 通过对外科重症监护病房(SICU)持续真菌感染发病率的监测,探讨预防及控制SICU侵袭性真菌感染措施.方法 对2003-2008年收住SICU患者的血、尿、痰、引流液标本进行真菌培养.结果 共入选患者3699例,其中检出真菌培养阳性并且确定侵袭性真菌感染患者75例,6年真菌感染发病率1.05%~2.63%,其中下呼吸道感染0.65%~2.01%、泌尿系感染0.3%~1.3%、血行感染0~0.8%;共检出86株真菌,主要为白色假丝酵母菌、光滑假丝酵母菌、热带假丝酵母菌,分别占46.51%、22.09%、13.95%.结论 6年来真菌感染的发病率未见明显增加,假丝酵母菌属为SICU主要侵袭性真菌感染菌株.

关 键 词:侵袭性真菌感染  外科重症监护病房  发病率

Surveillance to Invasive Fungal Infection in Surgical Intensive care Unit During 6-years
LIU Fang,AN You-zhong,WU Ying-hong,LI Shu,ZHANG Zhen-yu,MA Li,WANG Zhan-wei,FENG Shuang-yun. Surveillance to Invasive Fungal Infection in Surgical Intensive care Unit During 6-years[J]. Chinese Journal of Nosocomiology, 2009, 19(22)
Authors:LIU Fang  AN You-zhong  WU Ying-hong  LI Shu  ZHANG Zhen-yu  MA Li  WANG Zhan-wei  FENG Shuang-yun
Abstract:OBJECTIVE To surveillance invasive fungal infection rate in SICU, in order to direct intervention to prevent invasive fungal infection. METHODS The samples collected from SICU patients in our hospital between Jan 2003-Nov 2008 were cultured. RESULTS According to the diagnosis standard of nosocomial infections, 75 case of 3699 patients were isolated fungi. During 6-years invasive fungal infection rate is 2.027 %, (1.05 %-2.63%). Totally 86 fungi strains were isolated, the majority of them being Candida albicans, accounting for 46.51%; Can-dida glabrata 22.09%; Candida tropicalis 13.95%. CONCLUSIONS During 6-years, invasive fungal infection rate and incidence density do not increase. Candida are the major pathogens of fungal infections in SICU.
Keywords:Invasive fungal infection  SICU  Incidence
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