Lichen planus on the palms and soles

Case reports Five cases of palm and sole lichen planus (LP) taken from our series of 263 cases observed from 1985 to date are reported. Comments The clinical features of LP on the palms and soles are hyperkeratotic papules, erythematous patches, erosive lesions and also acrosyringeal LP. It has been hypothesized that betablocker drugs excreted by the ecerine if glands could influence the physiology of the excretory duct producing the acrosyringeal modification of LP. The authors evidence the association, in two patients, between erosive palm and sole LP and HCV-positive hepatopathy and also the association between LP erosive features and liver involvement.