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Dichloroacetate induces regulatory T‐cell differentiation and suppresses Th17‐cell differentiation by pyruvate dehydrogenase kinase‐independent mechanism |
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| Authors: | Naoyuki Makita Jun Ishiguro Keisuke Suzuki Futoshi Nara |
| Affiliation: | 1. Group III Biologics & Immuno‐Oncology Laboratories, Daiichi Sankyo Co. Ltd., Tokyo, Japan;2. Group III Pain & Neuroscience Laboratories, Daiichi Sankyo Co. Ltd., Tokyo, Japan |
| Abstract: | |
| Keywords: | dichloroacetate pyruvate dehydrogenase kinase reactive oxygen species Th17 Treg |