| The influence of modified electrocomulsive therapy on serum interleukin—6 in schizophrenic patients |
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| 作者姓名： | 杜宝国 吕路线 等 |
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| 作者单位： | [1]GerontologyDepartment,SecondAffiliatedHospital,XinxiangMedicalCollege,Xinxiang453002,HenanProvince,China [2]GerontologyDepartment,SecondAffiliatedHospital,XinxiangMedicalCollege,Xinxiang453002,HenanProvi |
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| 摘 要： | AIM：To explore the influence of modified electroconvulsive therapy on serum interleukin-6 in schizophrenic patients.METHOD:Testing change of serum IL-6 in 60 cases treated with MECT and 60 control cases treated with clozapine therapy by ELISA method. RESULTS:Serum IL-6 level before treatment of both groups was positive related to SAPS; serum IL-6 level wasn′t related to BPRS total score, factor score and SANS total fractions. IL-6 level of clozapine therapy group decrease apparently after treatment, and IL-6 level was apparently positive related to anxious depressed factor of BPRS; but there was no apparent difference in IL-6 level of MECT group between before and after treatment.CONCLUSION:To schizophrenic patients, clozapine can take effects of immune inhibit through inhibiting serum IL-6; MECT may have different mechanism.
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| 关 键 词： | 无抽搐电休克 精神分裂症 血清白介素6 影响 |
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