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肽疫苗修饰研究进展
引用本文:耿淼,吴玉章. 肽疫苗修饰研究进展[J]. 免疫学杂志, 2001, 17(Z1): 41-44
作者姓名:耿淼  吴玉章
作者单位:第三军医大学免疫学研究所,
基金项目:国家自然科学基金资助项目(39800170)
摘    要:随着免疫学和组合化学的进展,肽疫苗研究已取得了极大成功,但在对其实验与应用中发现肽疫苗存在许多缺陷,导致免疫原性相对较弱.国内外根据其不足进行了多种修饰,以改善其免疫原性.本文对一些常用修饰方法进行了综述.

关 键 词:肽疫苗  修饰  免疫原性
文章编号:1000-8861(2001)03(S)-0041-04
修稿时间:2001-05-30

Advances in modification of peptide vaccine
GENG Miao. Advances in modification of peptide vaccine[J]. Immunological Journal, 2001, 17(Z1): 41-44
Authors:GENG Miao
Abstract:With advances in immunology and combinational chemistry, there is great success on peptide vaccine. However, in many experiments, it was found that there is a lot of disadvantage which result in lowering of immunity. Thus a number of investigators had tried a variety of modifications to shorten peptide molecule, to improve its immunity. These methods are summed up in this paper.
Keywords:peptide vaccine  modification  immunity
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