Mechanical properties and biocompatibility of soluble eggshell membrane protein/poly(vinyl alcohol) blend films |
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Authors: | Yi Feng Lu Jian-Wei Guo Zhao-Xia Yu Jian |
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Affiliation: | Institute of Polymer Science and Engineering, Department of Chemical Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, P R. China. |
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Abstract: | Poly(vinyl alcohol) (PVA) has been blended with soluble eggshell membrane protein (SEP) to improve the mechanical properties of SEP film that is brittle. Tensile strength and elongation-at-break increase with increasing amount of PVA. When the SEP/PVA proportion is 1:1, a strong and flexible film is obtained, having a tensile strength of 22.7 MPa and elongation-at-break of 106%. Although scanning electron microscopy observation of the freeze-fractured cross-section shows microphase separation, interaction between SEP and PVA exists, as revealed by FT-IR. NIH3T3 cell culture demonstrates that SEP/PVA blend films with up to 50% of PVA show biocompatibility comparable to pure SEP film. |
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