| 藤茶总黄酮对免疫性肝损伤小鼠的保护作用 |
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| 引用本文： | 欧贤红,郑作文. 藤茶总黄酮对免疫性肝损伤小鼠的保护作用[J]. 哈尔滨医药, 2011, 31(1): 1+3-1,3 |
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| 作者姓名： | 欧贤红 郑作文 |
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| 作者单位： | 1. 广西省桂林医学院,广西,桂林,541004
2. 广西省中医学院,广西,南宁,530001 |
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| 摘 要： | 目的 探讨藤茶总黄酮(Tengeha flavonoids,TF)对卡介苗(BCG)加脂多糖(LPS)诱导的免疫性肝损伤小鼠的保护作用.方法 采用BCG加LPS诱导免疫性肝损伤小鼠模型,测定血清中ALT、AST、MDA、SOD等肝功能指标,对肝组织进行HE染色,光镜下进行组织病理学检查.结果 TF能明显降低肝损伤模型...
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| 关 键 词： | 藤茶总黄酮 免疫性肝损伤 抗氧化 |
Protective Effect of Flavonoids from Ampelopsis Grossedentata on Immunological Liver Injury in Mice |
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| OU Xianhong,ZHENG Zuowen. Protective Effect of Flavonoids from Ampelopsis Grossedentata on Immunological Liver Injury in Mice[J]. harbin medical journal, 2011, 31(1): 1+3-1,3 |
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| Authors: | OU Xianhong ZHENG Zuowen |
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| Affiliation: | OU Xianhong1,ZHENG Zuowen2(1.Guilin Medical University,Guilin 541004,China,2.Guangxi Traditional Chinese Medical University,Nanning 530001,China) |
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| Abstract: | Objective To investigate the effect of Tengcha flavonoids(TF) on immunological liver injury induced by BCG plus LPS in mice.Methods BCG plus LPS were used to produce immunological liver injury model in mice.Serum hepatic function indexes,such as ALT,AST,MDA and SOD were measure.Liver tissues were dyed with HE and histopathological changes in liver were observed under light microscope.Results TF inhibited significantly the increase of ALT,AST and MDA in serum while SOD was increased.Histopathological changes... |
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| Keywords: | Tengcha flavonoids Immunological liver injury Anti-oxidation |
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