| 急性冠状动脉综合征患者血总胆红素、尿酸水平分析 |
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| 引用本文： | 刘志勇,孙根义,刘玉洁,丛洪良,吕建国,王瑞莹.急性冠状动脉综合征患者血总胆红素、尿酸水平分析[J].临床心血管病杂志,2009,25(4). |
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| 作者姓名： | 刘志勇 孙根义 刘玉洁 丛洪良 吕建国 王瑞莹 |
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| 作者单位： | 天津市胸科医院心内科,天津,300051 |
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| 摘 要： | 目的:探讨急性冠状动脉综合征(ACS)患者血清总胆红素、尿酸(UA)水平的变化.方法:将238例ACS患者分为ST段抬高急性心肌梗死(STEMI)组,非ST段抬高急性心肌梗死(NSTEMI)组,不稳定型心绞痛(UAP)组,检测血清总胆红素、UA、血糖、血脂等生化指标,部分ACS患者行冠状动脉造影检查.109例冠状动脉造影检查未见冠状动脉明显狭窄者作为对照组.结果:ACS各组患者血清总胆红素、UA、血糖显著高于对照组,差异有统计学意义(P<0.01或P<0.05).STEMI组总胆红素、血糖显著高于NSTEMI组和UAP组患者,差异有统计学意义(P<0.01).1周后复查,ACS各组患者血清总胆红素明显回降,与对照组比较差异无统计学意义(P>0.05).结论:ACS患者血糖、UA升高,提示机体氧化应激加重;同时血清总胆红素升高,显示机体代偿性抗氧化程度加强.随病情逐渐稳定,胆红素回降.UA和胆红素可间接反映ACS机体氧化、抗氧化情况.胆红素对评估病情进程亦有一定帮助.
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| 关 键 词： | 急性冠状动脉综合征 胆红素 尿酸 |
Study of relationship between the levels of total serum bilirubin,uric acid and acute coronary syndrome |
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| LIU Zhiyong,SUN Genyi,LIU Yujie,CONG Hongliang,LV Jianguo,WANG Ruiying.Study of relationship between the levels of total serum bilirubin,uric acid and acute coronary syndrome[J].Journal of Clinical Cardiology,2009,25(4). |
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| Authors: | LIU Zhiyong SUN Genyi LIU Yujie CONG Hongliang LV Jianguo WANG Ruiying |
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| Abstract: | Objective:To study the relationship between serum total bilirubin,uric acid and coronary lesion in people with acute coronary syndromes.Method:Two hundred and thirty-eight patients with acute coronary syndromes were divided into the ST elevated myocardial infarction(STEMI) group,the non-ST elevated myocardial infarction(NSTEMI) group,the unstable angina pectoris(UAP) group.Some of them were undergone diagnostic coronary angiography.One hundred and nine patients undergoing diagnostic coronary angiography who... |
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| Keywords: | acute coronary syndrome bilirubin uric acid |
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