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Changes in cardiac innervation during maturation in long-term diabetes |
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| Authors: | Marija Bakovic Marina Juric Paic Elena Zdrilic Katarina Vukojevic Lejla Ferhatovic Ana Marin Natalija Filipovic Ivica Grkovic Livia Puljak |
| Affiliation: | 1. Laboratory for Neurocardiology, University of Split School of Medicine, Soltanska 2, 21000 Split, Croatia;2. Laboratory for Early Human Development, University of Split School of Medicine, Soltanska 2, 21000 Split, Croatia;3. Laboratory for Pain Research, University of Split School of Medicine, Soltanska 2, 21000 Split, Croatia |
| Abstract: | Diabetic autonomic neuropathy being a common complication of diabetes mellitus (DM) is related to an increased risk of cardiovascular mortality. However, mechanisms underlying changes of innervation density in affected hearts remain insufficiently understood. Hence, the aim of this study was to describe quantitative changes of intra-myocardial nerve terminals in hearts of diabetic rats of various ages. |
| Keywords: | Diabetes mellitus Innervation PGP 9.5 Neuropathy Heart |
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