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血管内皮细胞生长因子与大肠癌治疗
引用本文:丁杰,廖国庆. 血管内皮细胞生长因子与大肠癌治疗[J]. 国际病理科学与临床杂志, 2006, 26(6): 3-474
作者姓名:丁杰  廖国庆
作者单位:1. 贵州省人民医院普外科,贵阳,550002
2. 中南大学湘雅医院普外科,长沙,410008
摘    要:血管内皮细胞生长因子(VEGF)在大肠癌组织中高表达,与肿瘤血管生成,肿瘤细胞增殖、转移,肿瘤预后关系密切。目前各种针对VEGF及其受体开展的抑制肿瘤血管生成的药物研究广泛开展,有的已经批准上市,用于大肠癌的临床治疗,为大肠癌的治疗开辟了新的途径。

关 键 词:血管内皮细胞生长因子  大肠癌  治疗
文章编号:1673-2588(2006)06-0470-05
收稿时间:2006-06-20
修稿时间:2006-06-20

Vascular endothelial growth factor and treatmentof colorectal cancer
DING Jie,LIAO Guo-qing. Vascular endothelial growth factor and treatmentof colorectal cancer[J]. Journal of International Pathology and Clinical Medicine, 2006, 26(6): 3-474
Authors:DING Jie  LIAO Guo-qing
Affiliation:1.Department of General Surgery, Guizhou Provincial People’s Hospital, Guiyang 550002;
2.Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Abstract:Vascular endothelial growth factor(VEGF) highly expressed in colorectal cancer,and it's associated intimately with angiogenesis and prognosis of tumour,proliferation and metastasis of tumour cell.Nowadays many researches on drugs against angiogenesis of colorectal cancer aimed at VEGF and its receptor have been done wildly.Some has been approved to come into the market for the clinical treatment of colorectal cancer.
Keywords:vascular endothelial growth factor  colorectal cancer  treatment
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