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Neurofibromatosis in children with Rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma study IV
Authors:Sung Lillian  Anderson James R  Arndt Carola  Raney R Beverly  Meyer William H  Pappo Alberto S
Affiliation:Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Abstract:We identified all children enrolled in the Intergroup Rhabdomyosarcoma Study Group-IV with neurofibromatosis type I (NF1) and rhabdomyosarcoma. Among 1025 eligible patients, 5 (0.5 %) had NF1. Three children had relapses, two of whom died of progressive disease. Patients with NF1 and rhabdomyosarcoma should be treated with intensive contemporary therapy protocols.
Keywords:IRSG, Intergroup Rhabdomyosarcoma Study Group   NF1, Neurofibromatosis type I   RMS, Rhabdomyosarcoma
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